Planets governing President Bush are eclipsed and in an uncomfortable position, making his tenure controversial and his re-election bid unsuccessful, the soothsayers said on Friday, four days before the vote.
On the other hand, the planets of Democratic challenger Senator John Kerry were in the ascendant, ensuring him success in competitions.
"Saturn, which is the lord of health and fortune for President Bush, has been eclipsed by the Sun, which is unfortunate and gives him a clear defeat," Lachhman Das Madan, editor of a popular astrology magazine, told Reuters.
"Kerry will win," said Madan, who is also known as "the emperor of astrologers." "It is cosmic writ that George W. Bush cannot become president of United States again."
Ajai Bhambi, a senior astrologer and author of several books on the science of predictions, agreed.
"Kerry is likely to beat Bush in the final verdict," he told the New Indian Express newspaper.
Bejan Daruwalla, another top astrologer, told Reuters he had yet to calculate who would win Tuesday's election. But Bush, even if he won, would not be allowed by his planets to complete a full term, he said.
Astrology is extremely popular in India and many top politicians, businessmen and movie stars consult astrologers before taking important decisions.
Tuesday's vote is forecast to be one of the closest in American history. A Reuters/Zogby poll showed on Thursday that Bush was leading Kerry by 48 to 46 percent but the lead was well within the poll's margin of error.