In the mainstream daily newspaper comics this week, two characters have been crippled in GW2: a cousin of Rob WIlco from the strip "Get Fuzzy" and long-timer B.D. in "Doonesbury".
I couldn't help but be reminded of the art from the German Expressionists after World War One. Amputation was also a theme, albeit more graphically depicted. It was also, in the case of Ernst Ludwig Kirchner, a metaphor for sexual impotence (no ED medications back in the 1920s).
Trench warfare of WW1 would be a "political quagmire" by today's standards. Troops stuck for over a year amidst death and muck with little relief or hope. It would be interesting to see if that war of early last century isn't thematically used by cartoonists/artists of this one.